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The Top-Rated Joint Health Supplements of 2025

This website is owned and operated by Stingray Direct. Stingray Direct may receive compensation from companies featured when you purchase through provided links.

How We Found the Best Joint Support Supplements

Top 5 Joint Supplements

One of the fastest-growing supplement categories today is products that address joint discomfort, often stiffness, achiness, and limited flexibility. The good news is that the right joint support supplement can help support flexibility, mobility, and cartilage health while easing joint-related discomfort. Some formulas contain ingredients that can have you seeing results in as few as 5 days.

With roughly 92 million Americans reporting the inability to enjoy everyday aspects of their daily lives due to joint discomfort, it is no surprise that hundreds of joint support supplements are flooding the marketplace. We have all seen and heard so many TV, radio, and online ads from brands promising benefits, but the reality is that many fall short. To that end, some of the most advertised brands use ineffective generic ingredients with little clinical studies. Worse, many contain low-quality fillers that may have negative health consequences.

How To Pick A Good Joint Support Supplement &
Avoid the Junk

With so many choices, figuring out what to look for in a good joint support supplement can be challenging. To make your life a tad easier, we’ve done months of research and pulled together the key ingredients that can help ease joint discomfort, improve flexibility and mobility, and get you back to playing twister in no time!

This short guide is here to help you discover what to look for and steer clear of when it comes to your joint support needs. Plus, we’ll share a list of the five best joint support supplements available today!

Let’s take a moment to understand precisely how joint supplements work and why adding them to your daily routine is essential.

Joint Supplements:
What Are They All About?

Joints are the places in the body where two or more bones meet. They are made of bones and soft tissues, such as cartilage, tendons, ligaments, and nerves. From the smallest, most mundane tasks, like brushing your teeth, to exercising, playing pickleball, or golf, your joints make all movement possible.

As we age, our joints can be impacted by many things, and joint discomfort can accelerate with an injury or accident. For example, osteoarthritis is a degenerative ‘wear and tear’ joint disease that causes joints to naturally wear and tear down with time and use. Acute inflammation is another factor that greatly impacts overall joint health and can lead to swelling and discomfort. A compromised immune system or common viruses can also cause damage to your joints.4-6

The good news is the right active ingredients in a joint supplement can help repair worn-down joints, ease acute inflammation, and add lubrication while supporting the long-term health of your joints.

What Causes Joint Discomfort?

A Great Joint Support
Supplement Can:

Ease joint discomfort 14,15

Improve joint mobility 15

Ease acute inflammation 16

Enhance joint flexibility 14

Lubricate joints 18

Support cartilage health 19

Start improving joint function in 5 days 33

3 Things To AVOID
When Buying A Joint Support Supplement

1. TITANIUM DIOXIDE & OTHER CAPSULE COLORANTS

If you look closely at the label’s ingredient section, you’ll see “other ingredients” listed. This is where ingredients like Titanium Dioxide, FD&C Blue No. 1, Red 3, and other harmful ingredients can be hidden.

Titanium dioxide is widely used in many popular joint support supplements to give the capsules a uniform, bright white color, making them more visually appealing to consumers. However, the drawbacks of using this ingredient far outweigh the benefits. This additive has been associated with DNA damage, acute inflammation, liver and intestinal toxicity, an impaired immune system, and even adverse effects on the gut microbiome.20-22

While this ingredient is still allowed in the United States, the European Food Safety Authority (EFSA) declared it unsafe for consumption and, as of 2022, banned its use as an additive in supplements.

Similarly, a Public Health Advisory was issued in 2003 on the use of capsule colorants FD&C Blue Dye No. 1, a synthetic blue dye that’s used in many products, including supplements, candy, and cosmetics.23,24

While titanium dioxide, FD&C Blue No. 1, and Red 3 are widely prevalent in joint supplements, we recommend avoiding them and instead looking for a more consumer-health-focused brand that uses cleaner ingredients.

2. GLUCOSAMINE & CHONDROITIN

Glucosamine is a natural compound found in cartilage.

It’s often touted on supplement bottles as an all-star necessary ingredient for joint comfort. However, in many clinical trials, glucosamine was shown to be either ineffective or showed small and arguably clinically unimportant treatment effects.25

Often, brands combine glucosamine with chondroitin, which has also shown to be ineffective.26-29 In a 2016 study, 164 patients with knee discomfort due to osteoarthritis were either given a combination of glucosamine and chondroitin or received an identical placebo pill. The study was stopped early because those taking the supplement actually reported worse symptoms than those taking a placebo.30

This compelling research is why we advise you to look beyond these ingredients and seek out supplements with clinically backed, more efficacious ingredients.

3. ADDED CALORIES AND CARBOHYDRATES

While conducting extensive research, the team at Review Scout was shocked to discover that numerous joint supplements on the market today contain unnecessary calories and carbohydrates. When you see calories or carbohydrates listed on a supplement, it’s a stark indication that the supplement contains inflammatory-causing additives like gelatin, oils, sugar, starches, or sweeteners.

When a person has arthritis, the body is said to be in an inflammatory state. That’s why you want to avoid these harmful additives at all costs.

Along with titanium dioxide, FD&C Blue No. 1, and Red 3, we also recommend avoiding supplements that contain calories and carbohydrates and instead sticking to brands that omit these ingredients.

Top 4 Criteria For A Quality
Joint Support Supplement

Below are the four essential criteria and most effective ingredients to consider and identify on a supplement label before deciding which brand is best for your needs.

2025’s Top Joint Support Supplements

Our review encompassed 84 different joint support supplements, putting each through our rigorous Review Scout assessment process. To determine 2025’s Top 5 Joint Support Supplements, we looked for key ingredients that predicted effectiveness, overall safety, offered a solid return policy, and overall customer satisfaction.

#1 Stonehenge Health Dynamic Joint

A+

Overall Grade

#1 Stonehenge Health Dynamic Joint

  • OVERALL RATING 9.7/10
  • Predicted Effectiveness 9.8/10
  • Ingredient Quality 9.7/10
  • Value 9.5/10
  • Return Policy 9.8/10
  • User Rating 9.7/10
PROS
  • Contains the clinically tested AprèsFlex® Boswellia extract
  • Includes Type II Collagen as hydrolyzed chicken collagen and Collagen Types I, V, and X as eggshell membrane
  • Contains Methylsulfonylmethane (MSM)
  • Added Hyaluronic Acid and Turmeric
  • Contains 100% RDA Vitamin D & Vitamin C
  • No calories, carbohydrates, or capsule colorants
  • Verified 90-day 100% money-back return policy
  • Manufactured in the USA
CONS
  • Often out of stock due to high demand
Why We Chose It

Stonehenge Health’s Dynamic Joint is Review Scout’s top choice. This supplement has all 4 of the top criteria for a quality joint-supporting supplement.

Stonehenge Health’s Dynamic Joint contains fast-acting AprèsFlex® Boswellia serrata gum resin, so users can see improvements in joint comfort as early as 5 days. Additionally, this formula includes all four essential collagen types for joint health: I, II, X, and V. Type II is sourced from our recommended hydrolyzed chicken collagen, and Types I, V, and X are also premiumly sourced from eggshell membranes. Stonehenge Health’s Dynamic Joint also contains methylsulfonylmethane (MSM) and natural supportive ingredients, including hyaluronic acid for joint lubrication and turmeric for its anti-inflammatory properties. Plus, this formulation even has the added benefit of 100% of your recommended daily allowance (RDA) of Vitamin C and Vitamin D3.

Stonehenge Health is committed to providing clean ingredients to its customers. It does not contain synthetic fillers or artificial ingredients that add calories or carbohydrates. It also does not contain titanium dioxide, FD&C Blue No. 1, or Red 3.

Stonehenge Health also backs its products with a 90-day, no-questions-asked money-back guarantee.

As an added benefit, their products are clearly listed as being manufactured in the USA. We also like that they offer customers discounts on bundles.

Click on the link below to see their current specials.

*Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.

#2 Instaflex Advanced Joint Support

A-

Overall Grade

#2 Instaflex Advanced Joint Support

  • OVERALL RATING 8.7/10
  • Predicted Effectiveness 9.1/10
  • Ingredient Quality 8.8/10
  • Value 8.2/10
  • Return Policy 8.8/10
  • User Rating 8.6/10
PROS
  • Contains three of the four essential ingredients
  • Contains AprèsFlex Boswellia serrata and Type II Collagen
  • Contains hyaluronic acid and turmeric
  • Doctor formulated
  • Formula verified by third-party
CONS
  • Users complain of the large capsule size despite the bottle advertising a small pill
  • Contains titanium dioxide additive
  • Contains FD&C Blue Dye No. 1
  • Only a 30-day money-back guarantee
  • $2 per capsule
Why We Chose It

Instaflex is a doctor-formulated joint health supplement that we are pleased to see contains the superior form of AprèsFlex Boswellia serrata as well as additional joint-supporting nutrients, including hyaluronic acid and turmeric. The brand took additional steps to validate its formula with third-party testing. However, at $60 a bottle for a 30-day supply, it seems as if the customer is absorbing this cost. When you add in the cost of shipping, Instaflex Advanced Joint Support is over $2 per capsule, making this one of the most expensive joint supplements on the market.

Although it’s great that they included Type II collagen derived from chicken sternum cartilage, they left out Types I, V, and X and failed to include MSM.

Instaflex includes titanium dioxide in its capsule formulation, which is a concern for anyone concerned with their health. And arguably more alarming to us was their additional use of the harmful colorant, FD&C Blue Dye No. 1, clearly known to cause damage.

Although the product is marketed as having a small pill size, user feedback often points to the capsules being uncomfortably large, contrary to what is advertised. Furthermore, the product’s guarantee only covers 30 days, which may not be sufficient for users to assess its effectiveness fully.

*For detailed information, please refer to the manufacturer’s product website. Instaflex is a registered trademark of Direct Digital, LLC.

#3 Osteo Bi-Flex Triple Strength

B

Overall Grade

#3 Osteo Bi-Flex Triple Strength

  • OVERALL RATING 7.6/10
  • Predicted Effectiveness 8.8/10
  • Ingredient Quality 8.3/10
  • Value 6.8/10
  • Return Policy 6.1/10
  • User Rating 7.8/10
PROS
  • Contains MSM
  • Contains clinically backed Boswellia serrata
  • Contains collagen
  • Contains Hyaluronic Acid
  • 60-day return policy
CONS
  • No Turmeric
  • Users complain of large capsules
  • Contains titanium dioxide
  • Contains glucosamine & chondroitin
  • 10 calories and 2 carbohydrates per serving
Why We Chose It

Osteo Bi-Flex included 1500 mg of MSM and 100mg of Boswellia Serrata extract in its formulation. Their Boswellia Serrata extract is in the form of 5-LOXIN®. We appreciate that 5-LOXIN has been clinically tested and has similar anti-inflammatory properties for treating osteoarthritis and joint discomfort as AprèsFlex, used in our top-rated brand. However, this still ranked inferior to ApresFlex®. Our preferred AprèsFlex delivers enhanced bioavailability, which allows for greater efficacy at lower doses and faster relief from acute inflammation and joint discomfort.47

A disappointing discovery was that this supplement contains both calories and carbohydrates. One daily serving of Osteo Bi-Flex has 10 calories and 2 carbohydrates. We can only assume those carbohydrates and calories come from the extensive list of “other ingredients,” which includes titanium dioxide.

Although Osteo Bi-Flex provides a generous 60-day return policy, we noticed that this brand sells 80 capsule bottles. At their 2-capsule dose per day, users will inconveniently run out of servings mid-month. After just 40 days.

*Please refer to the manufacturer’s product website for detailed information. Osteo Bi-Flex is a registered trademark of Société Des Produits Nestlé S.A.

#4 SynoCell

B-

Overall Grade

#4 SynoCell

  • OVERALL RATING 7.5/10
  • Predicted Effectiveness 7.2/10
  • Ingredient Quality 7.8/10
  • Value 6.4/10
  • Return Policy 9.8/10
  • User Rating 6.2/10
PROS
  • Contains three of the four essential ingredients
  • Contains Boswellia Extract
  • Contains Methylsulfonylmethane (MSM)
  • Contains Hyaluronic Acid
  • 90 Day Return Policy
  • Doctor Backed
CONS
  • Contains glucosamine
  • Contains generic Boswellia Extract
  • No Collagen
  • Low Amazon rating
  • Users complain it doesn’t work
Why We Chose It

Synocell is a doctor-backed joint health supplement that we are pleased to see contains three of the four essential ingredients: Boswellia serrata, Methylsulfonylmethane (MSM), and additional joint-supporting nutrients, including hyaluronic acid. Although we were happy to see the addition of Boswellia serrata, this brand is lower on the list because they added a generic form versus the top two brands who used superior, fast-acting relief, AprèsFlex®Boswellia serrata. We were disappointed to see this product relies on less efficacious glucosamine as one of its hero ingredients, which research shows to be ineffective. Synocell also advertises that it contains both glucosamine and chondroitin, yet there is no chondroitin listed in the supplement facts, confusing consumers. Furthermore, this supplement contains shellfish(shrimp, crab, crayfish, lobster), which the glucosamine comes from, which is not good for people with shellfish allergies.

Many user reviews claim this product doesn’t work, which is probably why a very low Amazon rating of 3.4 out of 5 is a cause for concern.

We were happy that this product offers a 90-day return policy and contains no titanium dioxide, capsule colorants, or added calories or carbs.

*Please refer to the manufacturer’s product website for detailed information. Synocell is a registered trademark of KONSCIOUS LLC.

#5 Move Free Advanced Glucosamine Chondroitin MSM Joint Support Supplement

C

Overall Grade

#5 Move Free Advanced Glucosamine Chondroitin MSM Joint Support Supplement

  • OVERALL RATING 7.2/10
  • Predicted Effectiveness 6.7/10
  • Ingredient Quality 7.1/10
  • Value 6.6/10
  • Return Policy 8.8/10
  • User Rating 6.8/10
PROS
  • Contains 1500mg of MSM
  • Contains hyaluronic acid
CONS
  • No Boswellia Serrata
  • No Collagen
  • No Turmeric
  • Contains titanium dioxide
  • Relies on glucosamine & chondroitin as two of its hero ingredients
  • Contains modified corn starch adding 5 Calories to each capsule
  • 3-tablets per serving
Why We Chose It

Move Free has made a mark in the joint care market with its substantial 1500mg dose of MSM.

However, Move Free faces several challenges. Notably, it lacks Boswellia serrata extract, an essential anti-inflammatory agent that many top-tier joint supplements include. Instead, it relies on less efficacious glucosamine and chondroitin as two of its hero ingredients.

Their formula not only contains titanium dioxide as an additive but also includes modified corn starch, which adds 5 calories to each serving.

Their recommendation of three tablets per serving might also deter users.

What we found to be suspicious is the lack of readily available information on their return policy, leading us to believe there is none.

*Please refer to the manufacturer’s product website for detailed information. Move Free is a registered trademark of RB HEALTH (US) LLC.

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