Our Stonehenge Health® Dynamic Liver™ stands out as a top choice because it includes all four essential ingredients for liver support. This comprehensive formula features Siliphos® Phytosome Milk Thistle for maximum absorption, CoreBiome® for gut-liver axis support, 4’Liver® to protect liver cells from stress and damage, and N-Acetyl Cysteine (NAC), all at clinically effective doses.

Additionally, Stonehenge Health® Dynamic Liver™ is impressive and incorporates Ayurvedic liver support ingredients such as dandelion, ginger, and beetroot extract, which provide comprehensive liver support.

Stonehenge Health® Dynamic Liver™ is particularly noteworthy because it is one of the few products in the U.S. currently using 4’Liver® in its formula. This inclusion demonstrates the formulation team’s commitment to innovation rather than simply imitating existing products. It’s clear they are focused on discovering new advancements in liver health that deliver real results for consumers.

Stonehenge Health’s formula is verified as non-GMO, uses vegetarian capsules, and contains no additives, binders, or fillers. Additionally, Stonehenge Health® offers a no-questions-asked, 90-day money-back guarantee on their products.

*Please refer to the manufacturer’s product website for detailed information.

Hepagard Liver Support contains three of the four essential ingredients for liver health: Milk Thistle Extract (80% Silymarin ), NAC, and Dandelion Root Powder. While we appreciate that they use the active ingredient of the milk thistle, Silymarin, we don’t like that it’s included in a proprietary blend. Determining whether the product contains 5 or 300 mg of silymarin is impossible. Similarly, N-Acetyl Cysteine is part of this proprietary blend, raising uncertainty about the actual amount included, and if this amount is clinically significant for your health.

Artichoke Leaf Extract is another ingredient in their proprietary blend. The brand’s website references a 2018 study⁴³ indicating that it could reduce lipid levels. However, the dosage used in the study far exceeds that included in the supplement.

This product also has no support for the gut-liver axis and no 4’Liver®.

Hepagard contains the additive magnesium stearate, which some individuals report experiencing negative reactions to and feeling significantly better after removing from their diets. Some people may also be sensitive to or even allergic to magnesium stearate.

Hepagard has a limited 30-day return policy; we’d have preferred a 90-day return policy, especially since some customer comments on their site indicate that it takes at least two months to determine if the product is effective.

*Please refer to the manufacturer’s product website for detailed information. Hepagard is a registered trademark of Nutreance LLC

We were very impressed that Gaia Herbs Liver Cleanse contains silybum milk thistle. While we like that this brand contains this potent milk thistle seed extract, we don’t like that it’s included in a proprietary blend. We have no idea how much is included. We would have also wanted to see technology designed for maximum absorption, like the first brand on this list.

Although Gaia contains additional liver-supporting nutrients, including dandelion root and ginger, they are all part of a proprietary blend, making it difficult to determine the exact amounts of each ingredient and whether they are sufficient to support the product’s claims.

While we appreciate the inclusion of ingredients like Artichoke Leaf extract, which can benefit the gut, we would have preferred the addition of an ingredient like CoreBiome®, which has been specifically studied for its benefits to the gut-liver axis.

Although they offer a 45-day return policy, we prefer 90 days to allow more time to determine if the product meets your needs. We liked that this product is free from additives, fillers, and binders.

*Please refer to the manufacturer’s product website for detailed information. Gaia is a registered trademark of Gaia Herbs, inc.

Nation Health MD’s Liver Renew is a doctor-backed liver support supplement that we were pleased to see contains Dandelion Powder, Ginger Powder, and Beetroot. While we appreciate the inclusion of milk thistle and the amount listed, they do not indicate which, if any, active compound of the plant you are actually receiving. Furthermore, the amount of milk thistle included is extremely low, at just 50 mg.

Nation Health MD is one of the more expensive liver supplements on the market, which is why it’s disappointing to see that they use L-cysteine to cut costs instead of the superior form, N-acetyl cysteine (NAC), and that they use the additive magnesium stearate. Nation Health does include artichoke leaf extract, which may maintain digestive health by increasing friendly gut bacteria. However, we’d prefer an ingredient like CoreBiome®, which can strengthen the gut lining to help prevent harmful bacteria from reaching the liver.

This supplement contains the same ingredients that have been used for decades. While we recognize that these ingredients have benefits, we are more concerned about the brand’s lack of emphasis on incorporating new scientific advancements, like 4Liver, used by the first brand on this list.

We also examined the bold claims, including its ability to “fire up fat burning.” However, none of the ingredients in this product or their dosages could support the claim of promoting fat burning.

We were happy they offer a 1-year return policy, giving customers ample time to see if this works for them.

*Please refer to the manufacturer’s product website for detailed information. Nation Health MD is a registered trademark of Nation Health MD LLC

Why We Chose It

Dose has gained popularity in recent years thanks to extensive online marketing and a prominent presence at checkout counters in many specialty health stores. It is a daily 2-oz single-serving drink that contains one of our four essential liver health ingredients.

While we were pleased to see that this product contains Dandelion Root Extract and Ginger, we were disappointed to see milk thistle listed as part of a proprietary blend with no amount or standardization listed. Also, part of this proprietary blend is organic turmeric extract. Their primary marketing technique is to heavily tout that their turmeric is made with an organic bioavailable Curcumin, said to be 24x better absorbed by the body. Yet it’s impossible to verify if this is true because they do not disclose the name of this ingredient or offer insight into where they sourced this research. We prefer brands with more transparency.

We also noticed their signature orange flavor comes from orange juice concentrate. Orange juice from concentrate is produced by removing water from the fruit, whereas orange juice not from concentrate is freshly squeezed directly from the fruit. Juice concentrates are often utilized because they have a longer shelf life; however, the filtration process can strip some of the natural vitamins, fiber, and antioxidants found in the fruit. This seems counterintuitive to maintaining liver health. We also question their addition of thickener xanthan gum, which can cause gas and bloating.

Inconveniently, they sell a three-week supply for $99. When you do the math, a 30-day supply will cost you $141.43. That’s more than double the price of the first brand on our list, which has significantly higher-quality ingredients and no additives. We suggest you save your money on glorified orange juice.

They have a 30-day return policy limited to one money-back guarantee per product per person. We prefer a 90-day policy without limitations.

*Please refer to the manufacturer’s product website for detailed information. Dose is a registered trademark of EETHO BRANDS, INC.