Why We Chose It

Four Sigmatic Mushroom Blend Defend is a popular product that contains ten different mushrooms from fruiting bodies. A big plus for us was that this formula uses extracts, but we would have preferred to see them list the extracts’ concentration to understand the potency better.

While Four Sigmatic includes all five of our top mushrooms, when it comes to Lion’s Mane, one of the essential mushrooms for brain and immune health, they fell short by only offering a 150 mg dose. This dosage is significantly lower than our minimum recommended 750 mg and far lower than the number one ranked brand on our list, which has 1,000 mg of Lion’s Mane in a 4:1 extract.

This product comes in a powder form, which could be a great fit for those who enjoy mixing a daily concoction. We tend to prefer the capsule form of supplements as they are more convenient to take and help ensure that you stay on your daily regimen for optimal results. A common complaint amongst users is that, even when stored in the container provided, the powder quickly forms into a dense brick, making it unusable. Users have also reported the product having an undesirable musky taste.

It was good to see that Four Sigmatic offers a 90-day money-back guarantee. A growing topic amongst Four Sigmatic users is related to the 30 servings the product packaging claims. Some users have expressed frustration stating they were only able to get 15 servings per package. A lower number of doses could indicate that what might seem like a product with a relatively low purchase price, is in actuality, quite expensive.

*Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.